Tell your doctor if you are breast-feeding.
What should I know about storage and disposal of this medication?
Entadfi® (as a combination product containing Finasteride, Tadalafil) Generic name: tadalafil [ ta-DAL-a-fil ] Other brand names of tadalafil include: Adcirca, Cialis Drug class: Impotence medications Cialis relaxes muscles of the blood vessels and increases blood flow to particular areas of the body. Cialis is used to treat erectile dysfunction (impotence) and symptoms of benign prostatic hypertrophy (enlarged prostate). Another brand of tadalafil is Adcirca, which is used to treat pulmonary arterial hypertension and improve exercise capacity in men and women. Do not take Cialis while also taking Adcirca, unless your doctor tells you to. Do not take Cialis if you are also using a nitrate drug for chest pain or heart problems, including nitroglycerin, isosorbide dinitrate, isosorbide mononitrate, and some recreational drugs such as "poppers".
Drug forms and administration
Taking tadalafil with a nitrate medicine can cause a sudden and serious decrease in blood pressure. Some medicines can cause great britain drugs generic cialis unwanted or dangerous effects when used with Cialis. Tell your doctor about all your current medicines, especially riociguat (Adempas). Contact your doctor or seek emergency medical attention if your erection is painful or lasts longer than 4 hours. A prolonged erection (priapism) can damage the penis. Cialis is not approved for use by anyone younger than 18 years old. Cialis is usually taken only once per day. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Cialis Original | 20mg | 120 + 8 Pills | 497.29€ 473.61€ | |
| Cialis Generic | 20mg | 60 + 6 Pills | 117.76€ 112.15€ | |
| Cialis Super Active | 20mg | 10 Pills | 55.64€ 52.99€ | |
| Cialis Generic | 2.5mg | 180 + 10 Pills | 154.86€ 147.49€ | |
| Cialis Generic | 10mg | 360 + 10 Pills | 388.49€ 369.99€ | |
| Cialis Black | 80mg | 360 + 20 Pills | 639.78€ 609.31€ | |
| Cialis Generic | 5mg | 270 + 10 Pills | 205.81€ 196.01€ | |
| Cialis Professional | 20mg | 90 + 2 Pills | 241.49€ 229.99€ | |
| Cialis Generic | 60mg | 180 + 10 Pills | 313.11€ 298.20€ | |
| Cialis Generic | 2.5mg | 10 Pills | 28.51€ 27.15€ | |
| Cialis Super Active | 20mg | 90 + 10 Pills | 314.14€ 299.18€ | |
| Cialis Professional | 40mg | 90 + 2 Pills | 348.59€ 331.99€ | |
| Cialis Professional | 20mg | 60 + 2 Pills | 183.83€ 175.08€ | |
| Cialis Generic | 40mg | 20 Pills | 59.47€ 56.64€ | |
| Cialis Generic | 20mg | 30 + 4 Pills | 68.05€ 64.81€ |
Cialis can be taken with or without food. For erectile dysfunction, take Cialis just before sexual activity but not more than once per day. Cialis can help achieve an erection when sexual stimulation occurs. An erection will not occur just by taking a pill. Do not take Cialis for erectile dysfunction if you are taking Adcirca for pulmonary arterial hypertension.
- Generic Cialis must carry the same warnings and precautions as the brand.
- The reliability of a generic depends on the manufacturer and approval status.
- Switching from brand to generic Cialis should be discussed with a doctor.
- Generic Cialis provides the same active ingredients and effectiveness.
Store at room temperature away from moisture and heat.
- FDA approval confirms that generic Cialis is bioequivalent to the brand.
- The availability of generic Cialis increases the accessibility of ED treatment.
- Patients report similar satisfaction levels using generic and brand-name Cialis.
- Price differences make generic Cialis a popular choice among patients.
As Cialis is used as needed, you are not likely to be on a dosing schedule.
| Interaction | Description | Risk Level | Notes |
|---|---|---|---|
| Nitrates | Severe hypotension risk | High | Avoid combination |
| Alpha-blockers | Can cause blood pressure drop | Moderate | Use with caution |
| CYP3A4 Inhibitors | Increased Tadalafil levels | Moderate | Adjust dosage |
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Active Ingredient and Indications
If you are taking tadalafil for erectile dysfunction on a regular schedule, take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose or more than one dose per day to make up for a missed one. If you are taking tadalafil for PAH or BPH, take the missed dose as soon as you remember it. Do not take a double dose to make up for a missed one.
Serious side effects of tadalafil
pain in the stomach, back, muscles, arms, or legs sudden decrease or loss of vision (see below for more information) changes in color vision (seeing a blue tinge on objects or having difficulty telling the difference between blue and green) sudden decrease or loss of hearing (see below for more information) erection that lasts longer than 4 hours swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs Some patients experienced a sudden loss of some or all of their vision after they took tadalafil or other medications that are similar to tadalafil. The vision loss was permanent in some cases. It is not known if the vision loss was caused by the medication. If you experience a sudden loss of vision while you are taking tadalafil, call your doctor immediately or get emergency medical treatment. Do not take any more doses of tadalafil or similar medications such as sildenafil (Revatio, Viagra) or vardenafil (Levitra) until you talk to your doctor. Drinking alcohol with this medicine can cause side effects. Grapefruit and grapefruit juice may interact with tadalafil and lead to unwanted side effects. Avoid the use of grapefruit products while taking this medicine.
| Year of FDA Approval | Generic Manufacturer | Approved Dosages | Market Availability |
|---|---|---|---|
| 2017 | Mylan | 5 mg, 10 mg, 20 mg | Widely available |
| 2018 | Aurobindo | 5 mg, 10 mg, 20 mg | Limited regions |
| 2019 | Teva | 2.5 mg, 5 mg, 10 mg | Full market |
Get emergency medical help if you have signs of an allergic reaction to Cialis: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
| Country | Over-the-Counter (OTC) | Restrictions | Notes |
|---|---|---|---|
| USA | No | Prescription needed | Not OTC in US |
| Mexico | Yes | None | Widely available OTC |
| UK | No | Prescription required | No OTC status in UK |
Stop and get medical help at once if you have nausea, chest pain, or dizziness during sex.
How Cialis Works
Get medical help at once if you have nausea, chest pain, or dizziness during sex. Stop using Cialis and get emergency medical help if you have sudden vision loss. You should not take Cialis if you are allergic to tadalafil. Taking Cialis with certain other medicines can cause a sudden and serious decrease in blood pressure. Do not take this medicine if you also use: riociguat (to treat pulmonary arterial hypertension); or riociguat (to treat pulmonary arterial hypertension); or a nitrate drug (for chest pain or heart problems) such as nitroglycerin, isosorbide dinitrate, isosorbide mononitrate, or recreational drugs such as amyl nitrate or nitrite "poppers".
Other uses
a nitrate drug (for chest pain or heart problems) such as nitroglycerin, isosorbide dinitrate, isosorbide mononitrate, or recreational drugs such as amyl nitrate or nitrite "poppers". Some tadalafil can remain in your bloodstream for 2 or more days after each dose you take (longer if you have liver or kidney disease). To make sure this Cialis is safe for you, tell your doctor if you have ever had: angina (chest pain), high or low blood pressure; angina (chest pain), high or low blood pressure; pulmonary hypertension (unless you are taking tadalafil for this); pulmonary hypertension (unless you are taking tadalafil for this); a condition called pulmonary veno-occlusive disease (narrowing of the veins that carry blood from the lungs to the heart); a condition called pulmonary veno-occlusive disease (narrowing of the veins that carry blood from the lungs to the heart); liver or kidney disease (or if you are on dialysis); liver or kidney disease (or if you are on dialysis); vision loss, or retinitis pigmentosa (an inherited condition of the eye); vision loss, or retinitis pigmentosa (an inherited condition of the eye); a blood cell disorder such as sickle cell anemia, multiple myeloma, or leukemia; a blood cell disorder such as sickle cell anemia, multiple myeloma, or leukemia; a physical deformity of the penis (such as Peyronie's disease), or an erection lasting longer than 4 hours; a physical deformity of the penis (such as Peyronie's disease), or an erection lasting longer than 4 hours; health problems that make sexual activity unsafe. health problems that make sexual activity unsafe. Sudden vision loss has occurred in a small number of people taking medicines like tadalafil (Viagra or others). You could be having a life-threatening side effect. Stop using this medicine and call your doctor at once if you have: a light-headed feeling, like you might pass out; a light-headed feeling, like you might pass out; an erection is painful or lasts longer than 4 hours (prolonged erection can damage the penis); an erection is painful or lasts longer than 4 hours (prolonged erection can damage the penis); ringing in your ears or sudden hearing loss; or ringing in your ears or sudden hearing loss; or heart attack symptoms - chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating. heart attack symptoms - chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating. muscle pain, back pain, pain in your arms, legs, or back.
Release Form and Composition
Some patients experienced a sudden decrease or loss of hearing after they took tadalafil or other medications that are similar to tadalafil. The hearing loss usually involved only one ear and did not always improve when the medication was stopped. It is not known if the hearing loss was caused by the medication. If you experience a sudden loss of hearing, sometimes with ringing in the ears or dizziness, while you are taking tadalafil, call your doctor immediately. Call your doctor if you have any unusual problems while taking this medication If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online ( or by phone (1-800-332-1088).
2. They Have Different Price Points
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Dispose of unneeded medications in a way so that pets, children, and other people cannot take them. Do not flush this medication down the toilet. Talk to your pharmacist about take-back programs in your community. This is not a complete list of side effects and others may occur.
How should this medicine be used?
Visit the FDA's Safe Disposal of Medicines website for more information. Keep all medication out of sight and reach of children as many containers are not child-resistant. Place the medication in a safe location – one that is up and away and out of their sight and reach. In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.
How long does tadalafil remain effective?
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription. Keep a written list of all of the prescription and nonprescription (over-the-counter) medicines, vitamins, minerals, and dietary supplements you are taking. Bring this list with you each time you visit a doctor or if you are admitted to the hospital. You should carry the list with you in case of emergencies. You may report side effects to FDA at 1-800-FDA-1088.
- Many countries have approved generic Cialis for sale in local markets.
- The FDA requires generic Cialis to have the same strength, quality, and purity.
- Switching between brand-name and generic Cialis should be done with medical advice.
- The availability of generic Cialis has increased worldwide access to ED treatment.
Tell your doctor about all your current medicines and any you start or stop using, especially: medicines to treat erectile dysfunction or pulmonary arterial hypertension; medicines to treat erectile dysfunction or pulmonary arterial hypertension; antiviral medicine to treat hepatitis C or HIV/AIDS; antiviral medicine to treat hepatitis C or HIV/AIDS; drugs to treat high blood pressure or a prostate disorder; or drugs to treat high blood pressure or a prostate disorder; or Other drugs may interact with tadalafil, including prescription and over-the-counter medicines, vitamins, and herbal products.
Stay on track with Rx alerts & expert care
Most of these people already had certain eye problems or had high cholesterol, diabetes, coronary artery disease, a history of smoking, or were over 50 years old). It is not clear whether the medicine was the actual cause of vision loss. Cialis is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. It is not known whether tadalafil passes into breast milk or if it could affect the nursing baby.